Manny Pacquiao got knocked out cold by Juan Manuel Marquez in a stunning upset in Las Vegas.

After getting knocked down earlier in the fight, Pacquiao came back and seemed to have Marquez bleeding and on the ropes. But in the sixth round, Marquez caught Pacquiao with a brutal, brutal right hand.

One punch and that was it. Manny was out before he hit the mat.

It was a huge upset, and has massive repercussions for the sport, as a Pacquiao-Mayweather fight now loses a good bit of its luster.

Here’s the video: